《英文msh詞典》Cancer Syndrome,Hereditary
[入口詞] Cancer Syndrome,Hereditary
[主題詞] Neoplastic Syndromes,Hereditary
[英文釋義] The condition of a pattern of malignancies within a family,but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age,individuals may have more than one primary tumor,the tumors may be multicentric,usually more than 25 percent of the individuals in direct lineal descent from the proband are affected,and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.